Ahmet Tugrul Ozdemir

Research Member of Common Room

Postdoctoral Scientist in Systems Neurophysiology

Department of Pharmacology

tugrul.ozdemir@pharm.ox.ac.uk

Tugrul grew up in Ankara and studied molecular biology, genetics and psychology at Bilkent University and at University of California Davis. During his undergraduate studies, he volunteered at an autism training centre in Beijing, interned to study genes controlling retina development in fruit fly larvae at KU Leuven, explore translational regulation mechanisms underlying synaptic plasticity at Stanford University and helped characterise in vivo recorded and labelled GABAergic medial septal cells at the University of Oxford. He carried out his PhD in the group of Prof Thomas Klausberger at the Medical University of Vienna, where he studied divergent cellular and network dynamics in the prefrontal cortex underlying working memory and cognitive flexibility. In April 2019, he joined the group of Prof Peter Somogyi as a postdoctoral scientist at the University of Oxford, and his current research is funded by the European Research Council and Wellcome Trust.

Tugrul’s research seeks to identify neuronal mechanisms underlying the loss of the awareness of both time and space in neurodegenerative diseases. The cerebral cortex comprises many diverse types of nerve cells that work together in neural networks, or circuits, and their interactions enable us to create, store and recall memories. But how do these different types of neuron co-operate to serve cognitive behaviour? Combining in vivo single cell and multi-unit electrophysiology with novel single cell RNA sequencing methods, Tugrul aims to establish a systematic and comprehensive characterisation of the neuronal cell types both in healthy mice and in a neurodegenerative disease model.