Junior Research Fellow
Postdoctoral Researcher in Chemical Biology
Department of Chemistry
BSc Lebanese American Uni, DPhil Oxon
Martine Abboud is a Postdoctoral Researcher in Chemical Biology at the Department of Chemistry. Her DPhil work focused on the use of a wide range of ligand-observe and protein-observe NMR techniques, and other biophysical methods, to study two general classes of enzymes – the 2-oxoglutarate-dependent dioxygenases and the metallo-β-lactamases (MBLs) which are involved in the hypoxic response and antimicrobial resistance, respectively. Her work provided interesting information about the substrate selectivity of the dioxygenases and mechanistic insights into the MBLs. She is currently interested in the metabolic enzymes involved in cancer and tuberculosis, which share similarities, and the penicillin-binding proteins (PBPs) which are involved in bacterial cell wall biosynthesis and antibiotic resistance.
Martine completed her undergraduate studies at the Lebanese American University, Lebanon, where she received the President’s Award for academic excellence and leadership skills. In November 2013, she came to St John’s College, Oxford, as Sir Hans Krebs Memorial Scholar, Biochemical Society. She has undertaken her DPhil research in the Chemistry Research Laboratory under the supervision and guidance of Professor Christopher Schofield and Professor Timothy Claridge. In February 2017, she was awarded a Thesis Commendation from the Mathematical, Physical, and Life Sciences Division. She won several prestigious awards (from both academia and industry) among them are a Pfizer-sponsored award in the DPhil Poster Symposium in 2015 and a Hans Neurath Outstanding Promise Award from the American Protein Society, 2017. Her work to date has been presented at several international conferences and described in over 13 peer-reviewed journals.