Nicholas Harding

Research Member of Common Room

Principal Bioinformatician

The Wellcome Trust Centre for Human Genetics

Nick works as a principal bioinformatician on the Anopheles gambiae 1000 genomes (Ag1000G) project. His particular interest is integrating complex multifocal datasets to analyse and to understand vector populations, particularly evolution of drug resistance and subsequent gene flow between discrete populations.

Specifically, he has recently worked on phasing of haplotypes (ie determining which mutations are on which chromosome), which is a necessary step for analyses of recent selection and adaptive introgression. He has also worked on a statistical model for identifying runs of homozygosity in genomes where we have limited ability to ascertain variation, as well as numerous other analyses as part of the Ag1000G project.

Nick completed his PhD at the University of Manchester in statistical epidemiology before carrying out his post-doctoral training on genomic heterogeneity within prostate cancer with Dr Paul Boutros at the Ontario Institute for Cancer Research in Toronto, Canada. He also holds degrees in Biological Sciences from the University of Oxford and Genetic Epidemiology from the University of Sheffield.