Toryn Poolman

Research Member of Common Room

Research Associate

Endocrinology and Metabolism

toryn.poolman@ocdem.ox.ac.uk

Toryn is a post-doc in the Ray lab (https://www.rdm.ox.ac.uk/about/our-divisions/oxford-centre-for-diabetes-endocrinology-and-metabolism/oxford-centre-for-diabetes-endocrinology-and-metabolism-research/ray-group. His research focuses on trying to understand how steroids work and how they interact with our body clock. Cortisol, a hormone released from the adrenal glands peaks in the early morning (the wakening hormone) and is virtually absent in the evening. Corticosteroids (collective name for steroid hormones produced by the adrenal gland, including glucocorticoids and mineralocorticoids) have powerful anti-inflammatory and metabolic effects, which are the template for synthetic steroids used to treat inflammatory diseases, such as rheumatoid arthritis and asthma. However, their use is hindered by severe side effects.  Toryn’s interests are in using techniques to measure changes in all genes or proteins, using next generation sequencing or mass spectrometry. He is interested in all aspects of data science (mainly using the R programming language), particularly machine learning and other techniques to understand complex datasets.